Minimally invasive <i>in situ</i> bioprinting using tube-based material transfer

Abstract Minimally invasive in situ bioprinting can potentially enhance the advantages of bioprinting, allowing surrounding healthy tissue to be maximally preserved. However, requirements for such a device are manifold and challenging fulfill. We present an experimental platform consisting extrusion system based on tube mounted between syringe dispensing nozzle. investigated influence material transfer through printing outcome. The results showed that it is feasible form continuous filament print 3-dimensional structures using developed platform.